U.S. stocks mixed at close of trade; Dow Jones Industrial Average up 0.24%

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At the close in NYSE, the Dow Jones Industrial Average gained 0.24%, while the S&P 500 index fell 0.25%, and the NASDAQ Composite index declined 1.07%.

The best performers of the session on the Dow Jones Industrial Average were Johnson & Johnson (NYSE:JNJ), which rose 4.49% or 7.12 points to trade at 165.61 at the close. Meanwhile, UnitedHealth Group Incorporated (NYSE:UNH) added 3.24% or 15.98 points to end at 509.23 and Merck & Company Inc (NYSE:MRK) was up 2.83% or 3.08 points to 111.91 in late trade.

The worst performers of the session were Nike Inc (NYSE:NKE), which fell 2.26% or 2.79 points to trade at 120.90 at the close. Home Depot Inc (NYSE:HD) declined 2.13% or 6.29 points to end at 288.67 and Boeing Co (NYSE:BA) was down 1.82% or 3.90 points to 210.00.

The top performers on the S&P 500 were Phillips 66 (NYSE:PSX) which rose 6.26% to 104.43, Valero Energy Corporation (NYSE:VLO) which was up 6.01% to settle at 135.09 and Marathon Petroleum Corp (NYSE:MPC) which gained 5.48% to close at 132.71.

The worst performers were MarketAxess Holdings Inc (NASDAQ:MKTX) which was down 13.91% to 337.74 in late trade, Signature Bank (OTC:SBNY) which lost 8.93% to settle at 0.15 and Caesars Entertainment Corporation (NASDAQ:CZR) which was down 6.18% to 45.82 at the close.

The top performers on the NASDAQ Composite were Jowell Global Ltd. (NASDAQ:JWEL) which rose 146.47% to 0.42, Liminal BioSciences Inc (NASDAQ:LMNL) which was up 85.64% to settle at 6.72 and InflaRx N.V. (NASDAQ:IFRX) which gained 61.80% to close at 6.10.

The worst performers were Secoo Holding Ltd (NASDAQ:SECO) which was down 39.69% to 0.88 in late trade, BullFrog AI Holdings Inc Unit (NASDAQ:BFRG) which lost 32.00% to settle at 4.08 and Guardforce AI Co Ltd (NASDAQ:GFAI) which was down 31.56% to 8.89 at the close.

Falling stocks outnumbered advancing ones on the New York Stock Exchange by 1879 to 1097 and 91 ended unchanged; on the Nasdaq Stock Exchange, 2447 fell and 1163 advanced, while 161 ended unchanged.

Shares in InflaRx N.V. (NASDAQ:IFRX) rose to 52-week highs; gaining 61.80% or 2.33 to 6.10.

The CBOE Volatility Index, which measures the implied volatility of S&P 500 options, was up 0.42% to 19.08.

Gold Futures for June delivery was down 0.04% or 0.90 to $2,037.30 a troy ounce. Elsewhere in commodities trading, Crude oil for delivery in May fell 0.42% or 0.34 to hit $80.37 a barrel, while the June Brent oil contract fell 0.21% or 0.18 to trade at $84.76 a barrel.

EUR/USD was down 0.46% to 1.09, while USD/JPY fell 0.26% to 131.35.

The US Dollar Index Futures was up 0.34% at 101.61.