U.S. stocks lower at close of trade; Dow Jones Industrial Average down 0.65%

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At the close in NYSE, the Dow Jones Industrial Average fell 0.65%, while the S&P 500 index lost 0.55%, and the NASDAQ Composite index declined 0.27%.

The best performers of the session on the Dow Jones Industrial Average were Boeing Co (NYSE:BA), which rose 3.21% or 6.50 points to trade at 208.90 at the close. Meanwhile, Salesforce.com Inc (NYSE:CRM) added 2.40% or 5.99 points to end at 255.88 and Merck & Company Inc (NYSE:MRK) was up 1.56% or 1.25 points to 81.43 in late trade.

The worst performers of the session were Walgreens Boots Alliance Inc (NASDAQ:WBA), which fell 8.99% or 3.96 points to trade at 40.13 at the close. Home Depot Inc (NYSE:HD) declined 2.64% or 7.39 points to end at 272.18 and American Express Company (NYSE:AXP) was down 2.44% or 2.89 points to 115.78.

The top performers on the S&P 500 were Kohls Corp (NYSE:KSS) which rose 10.55% to 28.91, Capri Holdings Ltd (NYSE:CPRI) which was up 8.78% to settle at 32.78 and Macy’s Inc (NYSE:M) which gained 8.54% to close at 8.71.

The worst performers were Walgreens Boots Alliance Inc (NASDAQ:WBA) which was down 8.99% to 40.13 in late trade, CVS Health Corp (NYSE:CVS) which lost 8.85% to settle at 66.97 and Boston Scientific Corp (NYSE:BSX) which was down 8.52% to 34.79 at the close.

The top performers on the NASDAQ Composite were Riot Blockchain Inc (NASDAQ:RIOT) which rose 47.80% to 6.060, Lexicon Pharmaceuticals Inc (NASDAQ:LXRX) which was up 37.21% to settle at 1.77 and Miragen Therapeutics Inc (NASDAQ:MGEN) which gained 30.39% to close at 20.5500.

The worst performers were Brainstorm Cell Therapeutics Inc (NASDAQ:BCLI) which was down 66.16% to 4.04 in late trade, Westwater Resources Inc (NASDAQ:WWR) which lost 21.37% to settle at 4.930 and Goodrx Holdings Inc (NASDAQ:GDRX) which was down 20.95% to 36.93 at the close.

Rising stocks outnumbered declining ones on the New York Stock Exchange by 1544 to 1349 and 98 ended unchanged; on the Nasdaq Stock Exchange, 1387 fell and 1375 advanced, while 83 ended unchanged.

Shares in Riot Blockchain Inc (NASDAQ:RIOT) rose to 52-week highs; gaining 47.80% or 1.960 to 6.060. Shares in Goodrx Holdings Inc (NASDAQ:GDRX) fell to all time lows; losing 20.95% or 9.79 to 36.93.

The CBOE Volatility Index, which measures the implied volatility of S&P 500 options, was up 3.30% to 23.19.

Gold Futures for December delivery was down 0.16% or 2.95 to $1884.85 a troy ounce. Elsewhere in commodities trading, Crude oil for delivery in December rose 0.27% or 0.11 to hit $41.45 a barrel, while the January Brent oil contract rose 0.11% or 0.05 to trade at $43.87 a barrel.

EUR/USD was up 0.08% to 1.1863, while USD/JPY fell 0.35% to 104.19.

The US Dollar Index Futures was down 0.21% at 92.435.