U.S. stocks lower at close of trade; Dow Jones Industrial Average down 1.17%

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At the close in NYSE, the Dow Jones Industrial Average declined 1.17%, while the S&P 500 index fell 0.92%, and the NASDAQ Composite index fell 0.28%.

The best performers of the session on the Dow Jones Industrial Average were Apple Inc (NASDAQ:AAPL), which rose 2.11% or 6.07 points to trade at 293.80 at the close. Meanwhile, UnitedHealth Group Incorporated (NYSE:UNH) added 1.68% or 4.82 points to end at 292.47 and Boeing Co (NYSE:BA) was up 1.45% or 2.02 points to 141.02 in late trade.

The worst performers of the session were American Express Company (NYSE:AXP), which fell 5.07% or 4.87 points to trade at 91.25 at the close. Walgreens Boots Alliance Inc (NASDAQ:WBA) declined 4.56% or 2.07 points to end at 43.29 and Raytheon Technologies Corp (NYSE:RTX) was down 4.55% or 3.09 points to 64.81.

The top performers on the S&P 500 were ABIOMED Inc (NASDAQ:ABMD) which rose 12.98% to 191.25, Nielsen Holdings PLC (NYSE:NLSN) which was up 5.52% to settle at 14.73 and Facebook Inc (NASDAQ:FB) which gained 5.42% to close at 204.71.

The worst performers were Tapestry Inc (NYSE:TPR) which was down 12.73% to 14.88 in late trade, Textron Inc (NYSE:TXT) which lost 12.19% to settle at 26.36 and Molson Coors Brewing Co Class B (NYSE:TAP) which was down 11.18% to 41.01 at the close.

The top performers on the NASDAQ Composite were Exela Technologies Inc (NASDAQ:XELA) which rose 59.12% to 0.3550, Cesca Therapeutics Inc (NASDAQ:THMO) which was up 58.05% to settle at 11.49 and Midatech Pharma PLC ADR (NASDAQ:MTP) which gained 55.26% to close at 2.9500.

The worst performers were Second Sight Medical Products (NASDAQ:EYES) which was down 36.67% to 1.33 in late trade, Verona Pharma PLC ADR (NASDAQ:VRNA) which lost 28.26% to settle at 4.24 and Taronis Technologies Inc (NASDAQ:TRNX) which was down 23.73% to 0.195 at the close.

Falling stocks outnumbered advancing ones on the New York Stock Exchange by 2171 to 715 and 53 ended unchanged; on the Nasdaq Stock Exchange, 1982 fell and 683 advanced, while 54 ended unchanged.

Shares in Cesca Therapeutics Inc (NASDAQ:THMO) rose to 52-week highs; gaining 58.05% or 4.22 to 11.49.

The CBOE Volatility Index, which measures the implied volatility of S&P 500 options, was up 9.35% to 34.15.

Gold Futures for June delivery was down 1.21% or 20.70 to $1692.70 a troy ounce. Elsewhere in commodities trading, Crude oil for delivery in June rose 26.96% or 4.06 to hit $19.12 a barrel, while the July Brent oil contract rose 0.30% or 0.08 to trade at $26.75 a barrel.

EUR/USD was down 0.03% to 1.0952, while USD/JPY rose 0.01% to 107.19.

The US Dollar Index Futures was down 0.60% at 99.050.