U.S. stocks lower at close of trade; Dow Jones Industrial Average down 0.08%

Investing.com – U.S. stocks were lower after the close on Wednesday, as losses in the , and sectors led shares lower.

At the close in NYSE, the fell 0.08%, while the index fell 0.20%, and the index lost 0.30%.

The best performers of the session on the were Johnson & Johnson (NYSE:), which rose 1.75% or 2.33 points to trade at 135.17 at the close. Meanwhile, Cisco Systems Inc (NASDAQ:) added 0.93% or 0.43 points to end at 46.79 and Walt Disney Company (NYSE:) was up 0.85% or 1.10 points to 130.86 in late trade.

The worst performers of the session were Exxon Mobil Corp (NYSE:), which fell 1.71% or 1.19 points to trade at 68.23 at the close. Chevron Corp (NYSE:) declined 1.03% or 1.20 points to end at 115.11 and Microsoft Corporation (NASDAQ:) was down 0.82% or 1.17 points to 140.41.

The top performers on the S&P 500 were McKesson Corporation (NYSE:) which rose 4.83% to 144.84, JB Hunt Transport Services Inc (NASDAQ:) which was up 3.63% to settle at 115.65 and AmerisourceBergen (NYSE:) which gained 3.43% to close at 86.05.

The worst performers were Alexion Pharmaceuticals Inc (NASDAQ:) which was down 5.06% to 99.51 in late trade, Exelon Corporation (NASDAQ:) which lost 4.57% to settle at 44.91 and DXC Technology Co (NYSE:) which was down 3.90% to 27.87 at the close.

The top performers on the NASDAQ Composite were Bionano Genomics Inc (NASDAQ:) which rose 417.62% to 2.85, Achillion Pharmaceuticals Inc (NASDAQ:) which was up 72.04% to settle at 6.28 and Viveve Medical Inc (NASDAQ:) which gained 39.47% to close at 5.3000.

The worst performers were Titan Medical Inc (NASDAQ:) which was down 51.83% to 0.5250 in late trade, Titan Pharmaceuticals Inc (NASDAQ:) which lost 51.02% to settle at 0.1800 and Golden Bull Ltd (NASDAQ:) which was down 31.57% to 0.48 at the close.

Rising stocks outnumbered declining ones on the New York Stock Exchange by 1480 to 1376 and 108 ended unchanged; on the Nasdaq Stock Exchange, 1351 rose and 1259 declined, while 103 ended unchanged.

Shares in Titan Medical Inc (NASDAQ:) fell to 5-year lows; falling 51.83% or 0.5650 to 0.5250. Shares in Achillion Pharmaceuticals Inc (NASDAQ:) rose to 52-week highs; gaining 72.04% or 2.63 to 6.28. Shares in Titan Pharmaceuticals Inc (NASDAQ:) fell to 5-year lows; falling 51.02% or 0.1875 to 0.1800.

The , which measures the implied volatility of S&P 500 options, was up 1.03% to 13.68.

Gold Futures for December delivery was up 0.70% or 10.45 to $1493.95 a troy ounce. Elsewhere in commodities trading, Crude oil for delivery in November rose 0.32% or 0.17 to hit $52.98 a barrel, while the December Brent oil contract fell 0.03% or 0.02 to trade at $59.08 a barrel.

EUR/USD was up 0.02% to 1.1073, while USD/JPY rose 0.00% to 108.75.

The US Dollar Index Futures was down 0.27% at 97.738.

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